I agree with you Massypoos, LV wouldn't make a good standalone city. However I would very much like to see the return of it somewhere down the line; the garish neon bathing everything in sickly colours, the noise of the casinos, taking in a show (maybe that godawful magician from IV could return.) The desert in V is very small, i'd like a vast expanse to go crashing around in in a sand rail, getting caught in a sandstorm, peering into the horizon and not being able to see a thing except rocks and bushes, obviously Area 69 would be there too.
Basically I want an HD San Andreas with a map 10x bigger than the last, just like everyone else. That concept map a while back was a nice size. Still, a man can dream, a man can dream...