Indy

Just to review the current arguments: E-cigarettes help smokers quit and are better at doing so than other nicotine replacement therapies. E-cigarettes are safer for the person inhaling them than conventional cigarettes. E-cigarette vapour contains far less toxic products than conventional cigarettes. E-cigarette vapour does contain trace amounts of toxic product. However, this is claimed to be negligible to health. Some E-cigarettes are made poorly and may contain more nicotine than advertised. In my opinion, I can see how even minute amounts of toxicity released from E-cigarettes can make people uncomfortable. Therefore, whether E-cigarettes are allowed to be smoked in public places will probably remain a matter of debate for quite some time. However, I believe that E-cigarettes will have a significant benefit to public health and potentially reduce the financial burden on public-funded healthcare systems (e.g. NHS). Whether or not E-cigarettes will be recommended by healthcare professionals remains an area of uncertainty. Guidelines (e.g. NICE) will not provide any significant guidance for their use until further evidence can be attained. Despite this, I am in favour of using E-cigarettes as a replacement for conventional cigarettes, especially if one has the intention of quitting. This is further supported by the fact that it has been proven to be more efficacious than other nicotine replacement therapies. My main concern is that all available research on this area is relatively weak. However, the research that has been done does warrant for further, more rigorous research into this particularly interesting area of public health.

Tullius has no motives with Skyrim. He's following the Thalmor's orders and trying to kill Ulfric. Skyrim is already part of the Empire, it always has been. The Empire has been corrupt and all around weak since the last Dragonborn emperor died during the events of Oblivion, and the Great War only made it weaker. In siding with Ulfric and freeing Skyrim from the Empire, you free them from the Thalmor. A Stormcloak Skyrim is a neutral Skyrim, to an extent. They have no obligation to even acknowledge the Thalmor or their self-proclaimed authority. With the Empire defeated, the Thalmor don't have enough men in Skyrim to stop the Stormcloaks from driving them out, and they have nothing to gain from returning to Skyrim in force. Another war with the Aldmeri Dominion is inevitable, but the Empire is stuck licking the Dominion's boots until it grows a pair of Septim bloodline-sized balls. Until that time, a Stormcloak Skyrim is free from all that shit. Amazing how I ignore real world politics, but will rant about video game politics at great length... I'm interested to see how the rebellion will be written in future Elder Scrolls games. Regardless, I'd like to see the Stormcloaks (Skyrim) and Redguards (Hammerfell) form an alliance, and take the fight to Summerset Isle. However, if history dictates that the Imperials beat the rebellion, I'd like to see the Empire fighting the Thalmor, ultimately ending with Hammerfell coming to the aid of the Empire. Think WW2 The Second Great War would make a great setting for the next Elder Scrolls game.

Since 2008, the FDA has been trying to prevent e-cigarettes from entering the country. To date, 50 shipments have been refused, but this has not stopped distribution and sale of e-cigarettes. Canada fully banned the devices in March 2009. E-cigarette makers and distributors have argued that their devices are safer than real cigarettes, thereby mitigating the harm of smoking. Some have implied that their products help people quit smoking tobacco products. The FDA rejects both claims. Because the devices can deliver a dose of synthetic nicotine, the agency sees them as unapproved drug-delivery devices with unknown safety. And whether they can safely help people quit smoking is also unknown, while they have a clear potential to entice new smokers with their fruit and candy flavors. The FDA research is preliminary, and there may also be conflict of interests. Furthermore, I'm very skeptical of research that doesn't come from peer-reviewed journals. This is the only research paper that I've actually been able to find from this paragraph. Not surprisingly, it indicates that e-cigarettes actually help smokers quit: The primary finding was that the 6-month point prevalence of smoking abstinence among the e-cigarette users in the sample was 31.0% Read here: http://download.jour...79710007920.pdf Furthermore, all these preliminary studies are just the same study you've highlighted above. I need stronger evidence. Regardless, even if what they say is true, e-cigarettes are still a significantly healthier option than real cigarettes, which contain (literally) hundreds of carcinogens and tobacco. The only thing this indicates is that e-cigarettes need to be regulated more tightly. E-cigarettes that claim to have no nicotine should have NO nicotine. Why do COPD sufferers have a lesser effect from an apparent vasoconstrictor than non-smokers? Because the sample size is far too small to draw any significant conclusions. Everybody knows that Nicotine is linked to the development of lung cancer via reduced apoptosis. But nicotine alone is insignificant without carcinogens. Thus, this argument is only really valid in the face of real cigarettes. I'm not really sure what to make of any of this evidence, we need longer-term studies with larger sample sizes into the effects of e-cigarettes before any sound conclusions can be drawn. Furthermore, research into the chemical composition of e-cigarettes will provide an excellent insight into the potential pitfalls of yet another nicotine based therapy.

I would love to see evidence of that. From my research, I always thought that Nicotine had almost no long-term negative effects on health*. This is a genuine request, it might alter my opinion on Nicotine. Oxygen? *However, it is supposed to inhibit apoptosis, thereby promoting carcinogenesis.

Both factions are cunts. The imperials are loosely aligned with the Thalmor. Who are the royal cunts of Tamriel and should be dispatched at first sight. Don't even think about it, just kill them. On the other hand are the religiously oppressed racists, aka Stormcloaks. Choosing between the Thalmor lapdogs and the Nord facist army is difficult because neither is without severe flaws. Just a bit of history to help inform your decision. The Empire (Imperials) and Aldmeri Dominion (Thalmor) fought in the Great War. The Empire lost, and subsequently the White-Gold Concordat (treaty) was formed. As part of a treaty, they have had to ban Talos worship. If the Imperials stop rebellions, they may be able to strengthen and defeat the Aldmeri Dominion at a later date. On the other hand, none of this matters because the Redguards are badass. Learn yo history: http://elderscrolls.wikia.com/wiki/Great_War

Chronicle - 8.5/10 One of the best movies i've seen in a very long time. It's about three teenagers who gain superpowers, but it is not like your everyday superhero movie. I don't want to give anything away. This is a MUST SEE!

I like Black Keys, great advert music.

Breast of duck with plum sauce, and Ludovico Einaudi personally playing I Giorni. I would gladly die after that. Or this.

This. Sometimes I just use the horse to walk slowly through towns. Just so they know who's boss. It would have been great if they added satchels and storage to horses, as well as the ability to call your horse.

That's crazy.. I've gotten my foot run over before but it wasn't bad but I can't imagine how bad it would hurt happening to any other party of the body. And yeah that's some good advice I wish I would have taken. I'm about 5 weeks into letting my boxers fracture heal without medical attention and there's still a bone sticking up in my hand and my pinky knuckle is in a completely different spot than it used to be. Oh well, I figure it will probably wind up breaking again eventually since it didn't heal right, so next time I'll head to the ER right away The power of hindsight!

Yeah Supras are pretty good quality. There is so much variation as well, including colours and style. At the moment I have either navy Vaiders or Skytops, can't remember. But they do nice mid and low tops too. I really like Clae's as well. In particular the Russell and McQueen lines. http://clae.eu/collection

Jimmy Carr is probably the only comedian of his kind that I like (i.e. one liners). I prefer observational comedy or story-tellers.

Some of my favourite right now are: Louis C.K Kevin Hart Kevin Bridges Micky Flanagan I like both British and US stand-ups, some special mentions for Michael McIntyre and Aziz Ansari.

I find my vans and supras are pretty comfortable.

So, Barca destroyed Milan.

Stupid story short, my friend ran me over, hurt like a muthafucka. Just some medical advice, if you've fractured or broken a bone, please go to ER so that they can X-ray and fix it into place properly. Otherwise it may heal deformed.

That is a fucking awesome beard, I wish I could grow one

He's not coming back. Probably doesn't even realise the topic was moved. I think the 360 has better triggers on its controller. I hope PS4 fixes that.

Funny you say that, Nani and Welbeck were probably the best two players on the pitch before the card! Fergies tactics were working great, unfortunate about the red card. Mourinho showed again that he was a great tactician by subbing on Modric and changing the shape to exploit the sending off.

Brilliant car.

That's very interesting, I know about the Swiss Pikemen (from Age of Empires, I think!). I'm a Sikh, our warrior culture is immense and something that people should really read about, purely because it's so interesting! Our entire history is embroiled in last stands, it would make Leonidas proud. For example, the Battle of Saragarhi 1897. 21 Sikhs against 10,000 Afghans. Known as one of the greatest last-stands in all of military history, every single man gave his life, yet very few people know about the battle. Furthermore, unlike many of the older last-stands, this one was very accurately recorded, partly due to the nature of the battle and also due to the fact it was fairly recent. http://en.wikipedia.org/wiki/Battle_of_Saragarhi

I fucking love the germans. Been reading a lot about them, they have their foot in almost every western civilisation!

Well now we've entered the realm of philosophy, never really my forté. However, I did once read an excellent book that parallels with what you are saying. You may be familiar with the books maxim: "Nothing is true, everything is permitted." Assassins Creed took the motto from the novel, entitled Alamut. In fact, it's a story that has parallels with the matrix, but far less "out of this world". Basically, a (persian?) army commander convinces his troops that he can temporarily send them to heaven at will. He does this by secretly drugging them and sending them to the gardens behind the fortress, which he has mimicked to look like heaven. This way he earns their full obedience and convinces them that their death will send them straight to heaven. Ultimately, he fools them into a reality that does not exist.

Very eloquent, but I can't help but think that with so many theories and hypotheses being proven incorrect every year, it's hard not to wonder how much that we now know is wrong. The thing about that is. Everything we know about the world, and existence itself, is based on our limited perception of existence. Just about everything in life can possibly be false, because perhaps there is some major part of being that we missed due to our limited perception, which could dillute our understanding. The best example I can think of is the Matrix; you are led to believe it is 1999, you have a house, a job, an income etc. When in reality, you're a vegetable sitting in a test tube. Exactly, more the reason to challenge everything you learn. As opposed to accept that it is insurmountable and give up.

I agree, once again I'll leave you with Carl Sagan: